２００６年 原著論文、総説など

Miura, S., Tomitsuka, E., Kamei, Y., Yamazaki, T., Kai, Y., Tamura, M., Kita, K., Nishino, I., and Ezaki, O.: Overexpression of peroxisome proliferators-activated receptor γ co-activator-1α leads to muscle atrophy with depletion of ATP. Am. J. Pathol. 169, 1129-1139 (2006).

Nakatani, T., Katsumata, A., Miura, S., Kamei, Y., and Ezaki, O.: Effects of fish oil feeding and fasting on LXRα/RXRα binding to LXRE in the SREBP-1c promoter in mouse liver. Biochim. Biophys. Acta 1736, 77-86 (2005).

Yamazaki, T., Sasaki, E., Kakinuma, C., Yano, T., Miura, S., and Ezaki, O.: Increased VLDL secretion and gonadal fat mass in mice over-expressing liver acyl CoA: Diacylglycerol acyltransferase 1. J. Biol. Chem. 280, 21506-21514 (2005).

Miura, S., Tsunoda, N., Ikeda, S., Kai, Y., Cooke, D.W., Lane, M.D., and Ezaki, O.: Nuclear factor 1 regulates adipose tissues-specific expression in the mouse GLUT4 gene. Biochem. Biophys. Res. Commun. 325, 812-818 (2004).

Kamei, Y., Miura, S., Suzuki, M., Kai, Y., Mizukami, J., Taniguchi, T., Mochida, K., Hata, T., Matsuda, J., Aburatani, H., Nishino, I., and Ezaki, O.: Skeletal muscle FOXO1 (FKHR) transgenic mice have less skeletal muscle mass, down-regulated Type I (slow twitch/red muscle) fiber genes, and impaired glycemic control. J. Biol. Chem. 279, 41114-41123 (2004).

Miura, S., Tsunoda, N., Ikeda, S., Kai, Y., Ono, M., Maruyama, K., Takahashi, M. Mochida, K., Matsuda, J., Lane, M.D., and Ezaki, O.: Regulatory sequence elements of mouse GLUT4 gene expression in adipose tissues. Biochem. Biophys. Res. Commun. 312, 277-284 (2003).

Miura, S., Nagura, H., Sawamura, F., Tomita, I., Kawai, E., Mochizuki, N., Ikeda, M., Kraemer, F.B., and Tomita, T.: Sterol-mediated regulation of hormone-sensitive lipase in 3T3-L1 adipocytes. Lipids 38, 743-750 (2003).

Miura, S., Kai, Y., Ono, M., and Ezaki, O.: Overexpression of peroxisome proliferator-activated receptor  coactivator-1 α (PGC-1α) down-regulates GLUT4 mRNA in skeletal muscles. J. Biol. Chem. 278, 31385-31390 (2003).

Kamei, Y., Mizukami, J., Miura, S., Suzuki, M., Takahashi, N., Kawada, T., Taniguchi, T., and Ezaki, O.: A forkhead transcription factor FKHR up-regulates lipoprotein lipase expression in skeletal muscle. FEBS lett. 536, 232-236 (2003).

Ikeda, S., Miyazaki, H., Nakatani, T., Kai, Y., Kamei, Y., Miura, S., Tsuboyama-Kasaoka, N., and Ezaki, O.: Up-regulation of SREBP-1c and lipogenic genes in skeletal muscles after exercise training. Biochem. Biophys. Res. Commun. 296, 395-400 (2002).

Miura, S., Gan, J.W., Brzostowski, J., Parisi, M.J., Schultz, C.J., Londos, C., Oliver, B., and Kimmel, A.R.: Functional conservation for lipid storage droplet association among perilipin, ADRP, and TIP47 (PAT)-related proteins in mammals, drosophila, and dictyostelium. J. Biol. Chem. 277, 32253-32257 (2002).

Nakatani, T., Tsuboyama-Kasaoka, N., Takahashi, M., Miura, S., and Ezaki, O.: Mechanism for peroxisome proliferator-activated receptor-alpha activator-induced up-regulation of UCP2 mRNA in rodent hepatocytes. J. Biol. Chem. 277, 9562-9569 (2002).

Miura, Y., Chiba, T., Tomita, I., Koizumi, H., Miura, S., Umegaki, K., Hara, Y., Ikeda, M., and Tomita, T.: Tea catechins prevent the develoment of atherosclerosis in apoprotein E-deficient mice. J. Nutr. 131,27-32(2001).

Miura, Y., Chiba, T., Miura, S., Tomita, I., Umegaki, K., Ikeda, M. and Tomita, T.: Green tea polyphenols (flavan-3-ols) prevent oxidative modification of low density lipoproteins: An ex vivo study in humans. J. Nutr. Biochem. 11 (4), 216-222 (2000).

Tomita, T., Miura, Y., Chiba, T., Kawai, E., Umegaki, K., Miura, S., Koizumi, H., Ikeda, M. and Tomita, I.: Antiatherogenic effects of tea polyphenols (flavan-3-ols) in humans and apoE-deficient mice. Basic Life Sci. 66, 471-482 (1999).

Miura, S., Chiba, T., Mochizuki, N., Nagura, H., Nemoto, K., Tomita, I. and Tomita, T.: Cholesterol-mediated changes of neutral cholesterol esterase activity in macrophages. Mechanism for mobilization of cholesteryl esters in lipid droplets by HDL. Arterioscler. Thromb. Vasc. Biol. 17 (11), 3033-3040 (1997).

Chiba, T., Miura, S., Sawamura, F., Uetsuka, R., Tomita, I., Inoue, Y., Tsutsumi, K. and Tomita, T.: Antiatherogenic effects of a novel lipoprotein lipase-enhancing agent in cholesterol-fed New Zealand White rabbits. Arterioscler. Thromb. Vasc. Biol. 17 (11), 2601-2608 (1997).

Tomita, T., Miura, S., Chiba, T., Mochizuki, N., Nemoto, K.and Tomita, I.: Regulation of neutral cholesterol esterase activity in J774 A.1 macrophages. Ann. NY Acad. Sci. 811, 471-479 (1997).

Tomita, T., Sawamura, F., Uetsuka, R., Chiba, T., Miura, S., Ikeda, M. and Tomita, I.: Inhibition of cholesteryl ester accumulation by 17β-estradiol in macrophages through activation of neutral cholesterol esterase. Biochim. Biophys. Acta 1300, 210-218 (1996).

Miura, S., Watanabe, J., Sano, M., Tomita, T., Osawa, T., Hara, Y. and Tomita, I.: Effects of various natural antioxidants on the Cu2+-mediated oxidative modification of low density lipoprotein. Biol. Pharm. Bull. 18(1), 1-4 (1995).

Miura, S., Watanabe, J., Tomita, T., Sano, M., and Tomita, I.: The inhibitory effects of tea polyphenols (flavan-3-ol derivatives) on Cu2+ mediated oxidative modification of low density lipoprotein. Biol. Pharm. Bull. 17(12), 1567-1572 (1994).

Hirayama, T., Miura, S., Mori, Y., Ueta, M., Tagami, E., Yoshizawa, T. and Watanabe, T.: High-performance liquid chromatographic determination of 2-alkenals in oxidized lipid as their 7-amino-6-methylquinoline derivatives. Chem. Pharm. Bull. 39(5), 1253-1257 (1991).

平山晃久, 三浦進司, 植田緑, 田上恵理, 吉澤智子, 渡辺徹志. チオバルビツール酸反応性物質 precursor としての 2-alkenal 類：活性酸素ならびに過酸化物による 2-alkenal 類の酸化分解. 衛生化学 37, 211-217 (1991).

平山晃久, 三浦進司, 村井純子, 渡辺徹志. 油脂変質の新しい評価法としての 2,4-Diaminotoluene (DAT)-蛍光法による過酸化脂質中の α, β-不飽和アルデヒドの定量. 食衛誌 31, 508-512 (1990).

Hirayama, T., Miura, S., Araki, M., Takeo, Y. and Watanabe, T.: Fluorometric method for determination of 1, 2-unsaturated aldehydes in autooxidized lipids with 2,4-diaminotoluene. J. Assoc. Off. Anal. Chem. 73(4), 590-594 (1990).

江崎治、三浦進司：末梢・中枢における代謝・摂食制御因子：AMPキナーゼ, Clinical Neuroscience; 24 (8), 929-931, 2006

江崎治、三浦進司：骨格筋におけるエネルギー代謝：ミトコンドリア機能と肥満, Bio Clinica; 21(1), 31-36, 2006

江崎治、三浦進司：わかる実験医学シリーズ、生活習慣病がわかる−糖尿病・動脈硬化をはじめとする各疾患の分子機構と発症のメカニズム, 羊土社; 105-109, 2005

江崎治、三浦進司、山崎聖美、笠岡(坪山)宜代：インスリン抵抗性の治療：生活習慣改善の意義, ホルモンと臨床 ; 53(11); 89-98, 2005

江崎治、三浦進司、亀井康富 : 運動による筋肉の赤筋化、運動不足による白筋化機序，月刊カレントテラピー; 23(6), 23-26, 2005

三浦進司、江崎治 : 運動療法の分子メカニズム，現代医療; 36(9), 147-153, 2004

江崎治、三浦進司 :食事・運動療法のサイエンス，日本医師会雑誌; 131(11), 1789-1790, 2004

江崎治、三浦進司 :運動療法の分子メカニズム，別冊医学のあゆみ　糖尿病・代謝症候群２００４−２００６; 605-608, 2004

江崎治、三浦進司 :運動と糖代謝の分子メカニズム、筋肉組織の糖輸送機構を中心に，Diabetes Frontier,メディカルレビュー社:14 (1), 32-37, 2003.2

三浦進司、江崎治 :新時代の糖尿病学（３）運動負荷下の筋のグルコースおよび脂質利用のメカニズム，日本臨牀　増刊号９; 60; 267 –272, 2002

富田多嘉子、三浦進司、三浦有紀子、千葉　剛、池田雅彦 :茶の機能〜生体機能の新たな可能性〜，6.2.動脈硬化抑制作用，ｂ）動脈硬化発生機序，C）血小板凝集抑制作用，d）LDL酸化抑制作用，e）動脈硬化抑制作用 -動脈硬化モデルマウスでの研究-，学会出版センター; 128 –135, 2002.

Tomita, T., Miura, Y., Chiba, T., Kawai, E., Umegaki, K., Miura, S., Koizumi, H., Ikeda, M. and Tomita, I. : Antiatherogenic effects of tea polyphenols (flavan-3-ols) in humans and apoE-deficient mice. In: Plant Polyphenols 2: Chemistry, Biology, Pharmacology, Ecology Eds: Gross G.G, Hemingway R.W. and Yoshida T. pp471-482 Kluwer Academic / Plenum Publishers, New York, 1999

Tomita, I., Sano, M., Watanabe, J., Miura, S., Tomita, T., Yoshino, K. and Nakano, M. : Tea and its components as powerful antioxidants. in Oxidative Stress and Aging. Eds: Cutler, R.G., Packer, L., Bertram, J., and Mori, A. Birkhaüser Verlag Basel / Switzerland, pp355-365 (1995).